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Recall of Ferrari 488 GTB for another fire risk?

Fuel lines and Ferraris: a fiery combination that has resulted in numerous Maranello mid-mounted engines ending up on the internet for the wrong publicity. Just recently the V8 in the latest Ferrari California T was recalled in certain affected markets and now it has been confirmed that the Ferrari 488 GTB has similar problems with the fuel lines.

Redazione Carsengines 05 Mar 2016

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The University of Craiova Romania

And the cheerful management of European funds

Redazione Education 13 Oct 2009

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Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Resp

Silencing of Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Responsive Cancer Cells.Sabrina Rotolo 1, Simona Ceccarelli 1, Ferdinando Romano 1, Luigi Frati 1,2, Cinzia Marchese 1, Antonio Angeloni 1* 1 Dipartimento di Medicina Sperimentale, Universita` Sapienza di Roma, Roma, Italy, 2 Istituto Neurologico Mediterraneo ‘‘Neuromed, Pozzilli, ItalyAbstract : BackgroundKeratinocyte growth factor receptor (KGFR) is a splice variant of the FGFR2 gene expressed in epithelial cells. Activation of KGFR is a key factor in the regulation of physiological processes in epithelial cells such as proliferation, differentiation and wound healing. Alterations of KGFR signaling have been linked to the pathogenesis of different epithelial tumors. It has been also hypothesized that its specific ligand, KGF, might contribute to the development of resistance to 5-fluorouracil (5-FU) in epithelial cancers and tamoxifen in estrogen-positive breast cancers.Abstract : Methodology/Principal FindingsSmall interfering RNA was transfected into a human keratinocyte cell line (HaCaT), a breast cancer derived cell line (MCF-7) and a keratinocyte primary culture (KCs) to induce selective downregulation of KGFR expression. A strong and highly specific reduction of KGFR expression was observed at both RNA (reduction = 75.7%, P = 0.009) and protein level. KGFR silenced cells showed a reduced responsiveness to KGF treatment as assessed by measuring proliferation rate (14.2% versus 39.0% of the control cells, P

Redazione Health 03 Jul 2008

180.1K 0

Protection of the EU's Financial Interests: Commission welcomes European Parliament’s call for increased cooperation by Member States

The European Parliament adopted today a report on the protection of the EU’s financial interests. The European Commission welcomes this document as an important support in the fight against fraud affecting the EU budget. The report by rapporteur Francesco Musotto highlights the paramount importance of a constructive cooperation between the Member States and the Commission. It stresses the key responsibility of the Member States for the sound management of Community revenue and expenditure, in particular in the areas of agriculture and structural funds, and including the recovery of unduly spent sums. Finally, the report requests concrete follow-up actions, including measures against certain Member States

Redazione Economy 22 Feb 2008

298.6K 0

THE CITY WHICH IS INSIDE YOU

You live in your own inner city, which you bought in a silent auction. You were again unable to cancel your debts. Under your blackening eyelids you try to feel certain things. Without noticing your withdrawal from self, you leave for distant parts by using your ropes of thought like a ski-lift. Your shudders increase as you touch the numberless elements. In your screams at the moment when you feel the jolts from the echoes of your words crossing the threshold of your thought, you send birds fleeing before you. As you breathe, your roses wither. In your moments of madness, crystals fall from your roof. As your field of thought shrinks, your city expands. You exhaust yourself from running down the streets and avenues. As the lamps of your voltage machines alight upon your nights, your humans robotize themselves. The toads in your dirty waters frighten even the crocodiles. Your inner journey makes you grow older. Your internal cries amplify themselves. You manifest difficulties with forty paws. The auxiliary cells of your laboratories do not give you the opportunity to live any pleasurable moments. While the fear indicator inside you slackens you through and through, you have not even the possibility of speaking. With each movement of the clock, the seasons rip themselves out of your heart. Your solitude traverses your spirit without cease. by Ãœzeyir Lokman É¡AYCI Mantes la Ville - 22.09.2002 Traduit par by Yakup YURT en français French free verse translated into English free verse by F.J. Bergmann - 16.02.2003

Redazione World 30 Apr 2004

167.4K 0